Diabetes and What Medication?

Choosing the Right Medication for Diabetes 

Can you reverse type 2 diabetes? If you are considering a new medication for your diabetes, you may wonder which one is best for you. The choices can be overwhelming. This article will discuss Metformin, SGLT-2 inhibitors, GLP-1 receptor agonists, and Insulin pumps. If you’re unsure, it’s best to speak with your healthcare provider to determine the right treatment plan for your particular situation. Also, keep in mind that your treatment plan may need to change over time. 

Metformin 

While there are many benefits to metformin, it also comes with a host of potential side effects. If you’re taking metformin for diabetes, it’s important to know what to expect before you start. These side effects can include lactic acidosis, glycemia, nausea, diarrhea, constipation, and weight gain. If you experience any of these side effects, ask your doctor about switching to an extended-release preparation of the drug. 

SGLT-2 inhibitors 

Although SGLT-2 inhibitors are effective in reducing hyperglycemia, only about half of the diabetic patients meet recommended glucose levels. SGLT2 inhibitors are novel agents that act through different mechanisms to reduce blood glucose levels and are associated with acceptable safety profiles. Inhibitors of the sodium-glucose co-transporter 2 (SGLT2) block the reabsorption of glucose from the kidney. They also promote increased urine excretion of excess glucose from the blood. 

GLP-1 receptor agonists 

There is little debate about the safety of GLP-1 receptor agonists for diabetes. Even though these drugs are considered the first line of defense in diabetes management, there are still some safety concerns. These medications are considered to be less harmful than insulin, and the risk of low blood glucose is much lower than that of diabetes-induced cardiomyopathy. These drugs are also not recommended for people with thyroid cancer, pancreatitis, or multiple endocrine neoplasias. However, these risks do not make GLP-1 receptor agonists for diabetes a suitable first-line treatment for these patients. 

Insulin pump 

An insulin pump is a computerized device that allows patients to monitor their blood glucose levels and administer the right dose of insulin when they need it. While insulin is an essential part of treating diabetes, it can be uncomfortable and painful to administer injections daily. The benefits of an insulin pump make them an attractive option for those who want a more convenient solution to managing their diabetes. The pumps can also help people with diabetes manage their A1c levels and meet their blood sugar targets. 

Inhaled insulin 

Inhaled insulin is a powder form of rapid-acting insulin that is delivered to the lungs through oral inhalation. This type of diabetes medication is approved for the treatment of hyperglycemia in adults with diabetes. It is used alone or in combination with long-acting insulin in type 1 diabetic patients. The use of inhaled insulin is not recommended for patients with lung diseases or chronic hyperglycemia. 

Bile acid sequestrants 

Bile acid sequestrants are a class of diabetes medications that have been studied for their ability to improve glucose and insulin sensitivity. They may also improve the secretion of insulin. However, there are some caveats when using these drugs. In a clinical trial, colestimide was administered to a patient with type 2 diabetes, and postprandial glucose levels decreased. Colestimide was also found to improve cholesterol and lipid levels in the blood.