Will Diabetes Medication Cause Weight Loss?

Will Diabetes Medication Cause Weight Loss? 

Many people wonder will diabetes medications cause weight loss. The fact is, that the side effects of many of these drugs are similar to those of natural insulin. This is most common when you begin taking insulin, but weight gain can happen with other diabetes medications as well. Some of these medications will get rid of extra sugar in your body, and others will increase your body’s ability to produce insulin. Listed below are some common diabetes medications and their side effects. 

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Liraglutide 

The question of whether or not Liraglutide and diabetes medication cause weight loss is a complex one. While the conventional methods of weight-loss therapy, such as diet and exercise, have proven to be ineffective for most patients, new medications are closing the gap. Here’s an overview of some of these options. Ultimately, it will depend on the individual’s medical history and the specific drug they take. 

Wegovy 

While there is a high level of uncertainty surrounding this new drug, one thing is certain: it will be effective. A study conducted by Novo Nordisk revealed that a diabetes drug called Wegovy could help reduce the burden of high blood pressure, diabetes, and heart disease. While the study was small, it did identify a potential benefit for patients: weight loss. Studies show that a loss of just 5 to 10 percent of body weight reduces cardiovascular disease risks. This type of drug works by mimicking the effects of a hormone in the brain called GLP-1, which is associated with weight loss. It is important to note that the dosage of Wegovy must be increased gradually over 16 to 20 weeks. 

SGLT2 inhibitors 

Whether SGLT2 inhibitors and diabetes medications cause weight loss is not clear yet. A recent meta-analysis of two controlled trials concluded that both treatments significantly reduced BMI. In both studies, SGLT2 inhibitors were more effective than placebo. In the final meta-analysis, SGLT2 inhibitors were statistically significantly better than placebo. However, the study was downgraded one level because of its indirectness. 

Metformin 

One of the benefits of metformin is that it reduces the hunger signals that cause people to eat. One study of women with type 2 diabetes who were taking the drug found that the highest dosage group experienced significantly less hunger and ate less than the other groups. While these findings are encouraging, more research is needed to determine if metformin can reduce body weight. Here is a breakdown of the benefits of metformin and obesity. 

GLP-1 receptor agonists 

Some diabetes medications can cause weight gain in some patients. These drugs increase the level of a hormone called glucagon in the body, which regulates glucose and appetite. GLP-1 receptor agonists, or GLP-1 RAs, mimic the actions of this hormone. They slow the rate at which food is digested, which prevents blood sugar spikes after meals. They also increase the production of insulin, which is released when the body’s glucose level rises. GLP-1 RAs also block the release of sugar from the liver, which is a natural source of glucose.